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| Product Name | Niclosamide (ethanolamine salt) |
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| Description | Purity >98%. Niclosamide is an antihelminthic compound that affects mitochondrial metabolism in parasitic worms. It specifically inhibits the signal transducer and activator of transcription 3 (IC50 = 0.25 µM) and stimulates autophagy by reversibly inhibiting mTORC1 signaling (complete inhibition of S6K phosphorylation at 3 µM). Niclosamide ethanolamine is a more water soluble, salt version of niclosamide that has been used to increase energy expenditure and lipid metabolism in mice. At 125 mg/kg/day, niclosamide ethanolamine prevented high-fat diet-induced hepatic steatosis and insulin resistance and improved glycemic control in db/db mice. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-benzamide compd. with 2-aminoethanol, Bayluscide, NEN |
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| Gene, Accession, CAS # | CAS: 1420-04-8 |
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| Catalog # | LS-H8997 |
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| Order / More Info | Niclosamide (ethanolamine salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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