| 产品详情 |
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| Product Name | Nicorandil |
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| Description | Purity >98%. Nicorandil is a nicotinamide-nitric oxide ester with vasodilatory and cardioprotective effects. It is best known as a potassium channel activator that targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (EC50 = 10 µM). In addition to driving dilation of peripheral and coronary arterioles, K+ channel activation by nicorandil delays the induction of mitochondrial permeability transition in response to oxidative stress. Nicorandil can also act as a nitric oxide donor, increasing intracellular cGMP production leading to venodilation and pain suppression. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-(nitrooxy)ethyl]-3-pyridinecarboxamide, 2-Nicotinamidoethyl nitrate, SG-75 |
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| Gene, Accession, CAS # | CAS: 65141-46-0 |
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| Catalog # | LS-H8996 |
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| Order / More Info | Nicorandil from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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