产品详情 |
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Antigenic Specificity | MLK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MLK1 Polyclonal Antibody. MLK1 is a MLK(MAP3K) type protein kinase. The catalytic domain of mixed-lineage kinases (MLKs) kinases have amino acid sequence similarity to both the tyr-specific and the ser/thr-specific kinase classes. In addition to thee unusual nature of the kinase catalytic domains, MLK1 and MLK2 contain 2 leu/ile-zipper motifs and a basic sequence near their C-termini. MLK1 is a member of the neuronal apoptotic JNK/c-Jun pathway acting between Rac1/Cdc42 and MKK4 and -7 in death signaling. MLK1 expression has been documented in human epithelial tumor cell lines of colonic, breast and esophageal origin. |
Immunogen | n/a |
Other Names | Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K9; MLK1, PRKE1 |
Gene, Accession # | Entrez: 338372, 4293, 500690; Uniprot: P80192, Q3U1V8 |
Catalog # | PA5-15105 |
Price | |
Order / More Info | MLK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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