| 产品详情 |
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| Antigenic Specificity | MLL1 |
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| Clone | BL-175-7E8 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 20 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 10 µl/0.5 mg lysate, Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MLL1 Recombinant Monoclonal Antibody (BL-175-7E8). KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis. It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation. KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity. It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has h |
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| Immunogen | n/a |
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| Other Names | ALL-1; Trithorax-like protein |
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| Gene, Accession # | Entrez: 4297; Uniprot: Q03164 |
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| Catalog # | A700-010-T |
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| Price | |
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| Order / More Info | MLL1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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