| 产品详情 |
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| Antigenic Specificity | MLLT1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:20-1:100, Western Blot: 1:1,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MLLT1 Polyclonal Antibody. Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11;19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids. |
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| Immunogen | n/a |
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| Other Names | CTC-503J8.6, ENL, ENL/MLL fusion, LTG19, MLL/ENL fusion protein, MLLT1/MLL fusion, myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 1, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1, YEATS domain-containing protein 1, YEATS1 |
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| Gene, Accession # | Entrez: 4298; Uniprot: Q03111 |
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| Catalog # | A302-268A-M |
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| Price | |
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| Order / More Info | MLLT1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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