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| Antigenic Specificity | MLLT10 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MLLT10 Polyclonal Antibody. Translocations affecting chromosome 11q23 involve many partner chromosome regions and occur in various leukemias. The 11q23 gene involved in the translocations is MLL. MLLT10 is the partner gene to MLL1 involved in t(10; 11)(p12; q23) translocations. In an analysis of two leukemia patients, the in t(10; 11)(p12; q23) translocation fuses MLL1, a SET domain containg histone methyltransferase, to the MLLT10 gene. The MLLT10 gene encodes a predicted 1,027-amino acid protein containing an N-terminal zinc finger and a C-terminal leucine zipper domain. The MLLT10 gene is one of the few MLL partner genes to be independently rearranged with a third gene in leukemia, the CALM gene in the t(10; 11)(p12; q14) translocation. |
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| Immunogen | n/a |
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| Other Names | Protein AF-10; ALL1-fused gene from chromosome 10 protein; MLLT10; AF10 |
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| Gene, Accession # | Entrez: 17354, 361285, 8028; Uniprot: O54826, P55197 |
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| Catalog # | PA5-75235 |
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| Price | |
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| Order / More Info | MLLT10 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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