产品详情 |
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Antigenic Specificity | Glutamine Synthetase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamine Synthetase Polyclonal Antibody. Glutamine Synthetase (GS) catalyzes the conversion of ammonia and glutamate to glutamine. This reaction consumes a molecule of ATP: Glutamate + NH4+ + ATP = Glutamine + ADP + Pi. GS is found in astrocytes as an octamer of identical ~45kDa subunits. Most well known function of GS is the detoxification of brain ammonia. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, partic |
Immunogen | n/a |
Other Names | Glutamate-ammonia ligase, GS |
Gene, Accession # | Entrez: 14645, 24957, 2752; Uniprot: P09606, P15104, P15105 |
Catalog # | LF-PA0100 |
Price | |
Order / More Info | Glutamine Synthetase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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