| 产品详情 |
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| Antigenic Specificity | RIG-I |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIG-I Polyclonal Antibody. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. RIG-I contains RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, RIG-I triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). Thi |
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| Immunogen | n/a |
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| Other Names | Probable ATP-dependent RNA helicase DDX58; DEAD-box protein 58; Retinoic acid-inducible gene 1 protein; RIG-1; RIG-I; DDX58; |
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| Gene, Accession # | Entrez: 23586; Uniprot: O95786 |
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| Catalog # | PA5-11727 |
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| Price | |
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| Order / More Info | RIG-I Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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