| 产品详情 |
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| Antigenic Specificity | RIM3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 1.25 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIM3 Polyclonal Antibody. Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity. |
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| Immunogen | n/a |
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| Other Names | Regulating synaptic membrane exocytosis 3, NIM3, RIM3 |
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| Gene, Accession # | Entrez: 100068020, 100358798, 100714524, 242662, 519929, 563414, 607486, 65025, 9783; Uniprot: Q80U57, Q9JIR3, Q9UJD0 |
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| Catalog # | PA5-40964 |
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| Price | |
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| Order / More Info | RIM3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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