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| Product Name | Recombinant Bovine coronavirus Hemagglutinin-esterase (HE) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 47.7kDa. Full Length of Mature Protein: 19-424aa. N-terminal 6xHis-tagged. Bovine coronavirus (strain Mebus) (BCoV) (BCV). Structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. Ses to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune syst. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | E3 glycoprotein |
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| Gene, Accession, CAS # | HE, UniProt: P15776 |
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| Catalog # | RPC20253 |
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| Order / More Info | Recombinant Bovine coronavirus Hemagglutinin-esterase (HE) from BIOMATIK |
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| Product Specific References | n/a |
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