| 产品详情 |
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| Antigenic Specificity | TEK |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:2500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TEK Polyclonal Antibody. The endothelium-specific receptor tyrosine kinase 2 binds and interacts with angiogenic proteins. In acute inflammation, TIE2 signals vascular endothelial cells to stop early leakiness in vessels. This interaction depends partly upon VEGF, PLGF and PDGF. In pregnancy, vascular remodeling is initiated and mediated by VEGF and PLGF; however, recent studies demonstrate that failure of effective vascular remodeling in pre-eclampsia is associated with the erroneously low production of soluble TIE2. Following cerebral stroke, TIE2 production is also critical for appropriate vascular endothelial cell migration and differentiation in response and repair mechanisms. In most cases, damage caused by diabetes, stroke, hypoxia a |
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| Immunogen | n/a |
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| Other Names | CD202B, TIE-2, TIE2, VMCM, VMCM1, angiopoietin-1 receptor, endothelial tyrosine kinase, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, tunica interna endothelial cell kinase, tyrosine kinase with Ig and EGF homology domains-2, tyrosine-protein kinase receptor TEK, tyrosine-protein kinase receptor TIE-2 |
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| Gene, Accession # | Entrez: 21687, 7010; Uniprot: Q02763, Q02858 |
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| Catalog # | PA5-23082 |
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| Price | |
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| Order / More Info | TEK Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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