产品详情 |
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Antigenic Specificity | TEM5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 2-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TEM5 Polyclonal Antibody. Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates |
Immunogen | n/a |
Other Names | TEM5; G-protein coupled receptor 124; tumor endothelial marker 5 |
Gene, Accession # | Entrez: 100363275, 25960; Uniprot: Q96PE1 |
Catalog # | PA5-20441 |
Price | |
Order / More Info | TEM5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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