产品详情 |
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Antigenic Specificity | TEM7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TEM7 Polyclonal Antibody. Tumor endothelial marker 7 (TEM7) was identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues. Further experiments verified TEM7 was highly expressed in the endothelium of numerous other cancer types including breast, lung and brain tumors. At least four isoforms of TEM7 are known to exist; these include intracellular, secreted, and membrane-bound forms. A homologous protein, TEM7R (also known as PLXDC2), acts as a binding partner to TEM7 and is also abundantly expressed in the endothelium of malignant colorectal cancer but is absent or rare in normal colon mucosa. High expression of TEM7 is associated with metastasis and poor survival o |
Immunogen | n/a |
Other Names | TEM3, TEM7; 2410003I07Rik; plexin domain-containing protein 1; tumor endothelial marker 3; tumor endothelial marker 7 |
Gene, Accession # | Entrez: 303505, 57125, 72324; Uniprot: Q8IUK5, Q91ZV7 |
Catalog # | PA5-20427 |
Price | |
Order / More Info | TEM7 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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