| 产品详情 |
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| Antigenic Specificity | TEM8 |
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| Clone | 200C1339 (SB20) |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:10-1:500, Immunofluorescence: 1:10-1:500, Immunohistochemistry (Paraffin): 2-5 µg/mL, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TEM8 Monoclonal Antibody (200C1339 (SB20)). Recently, using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9). Based on TEM8s interaction with the C5 domain of collagen a3(VI), a protein also preferentially expressed in tumor endothelium, it is thought that TEM8 plays an important role in tumor angiogenesis. |
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| Immunogen | n/a |
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| Other Names | TEM8 |
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| Gene, Accession # | Entrez: 84168; Uniprot: Q9H6X2 |
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| Catalog # | MA1-41059 |
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| Price | |
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| Order / More Info | TEM8 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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