产品详情 |
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Antigenic Specificity | Tenascin C |
Clone | 4C8MS |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA: Assay-Dependent, Flow Cytometry: 1 µg/1x10^6 cells, Immunocytochemistry: 1:10-1:500, Immunofluorescence: 1:10-1:500, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:50 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tenascin C Monoclonal Antibody (4C8MS). In most tissues of adults, tenascin C is rarely present at significant levels. However, in developing tissues, or tissues experiencing a fast rate of growth, tenascin C is upregulated. This effect is particularly evident when this extracellular matrix glycoprotein is found in abundance in tissues responding to injury or infection. When muscular pH is increased, tenascin C production also increases. Prostate smooth muscle cells produce extra tenascin C when responding to LPS infection. In fibrosis and stenosis, tenascin C expression levels are markedly increased, and the protein seems to function as a mobilizer of immune cells responding to tissue damage and repair. In COPD, likewise, tenascin C expres |
Immunogen | n/a |
Other Names | 150-225, GMEM, GP, HXB, JI, TN, TN-C, GP 150-225, cytotactin, glioma-associated-extracellular matrix antigen, hexabrachion (tenascin), myotendinous antigen, neuronectin, tenascin, tenascin-C isoform 14/AD1/16 |
Gene, Accession # | Entrez: 116640, 21923, 3371; Uniprot: P24821, Q80YX1 |
Catalog # | MA5-16086 |
Price | |
Order / More Info | Tenascin C Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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