产品详情 |
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Antigenic Specificity | TEP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TEP1 Polyclonal Antibody. Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression level |
Immunogen | n/a |
Other Names | TLP1, TP1, TROVE1, VAULT2, p240; TROVE domain family, member 1; p80 telomerase homolog; telomerase protein 1; telomerase protein component 1 |
Gene, Accession # | Entrez: 21745, 64523, 7011; Uniprot: O08653, P97499, Q99973 |
Catalog # | PA5-20354 |
Price | |
Order / More Info | TEP1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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