产品详情 |
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Antigenic Specificity | NRG1 |
Clone | 147705 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 500 µg |
Concentration | lyophilized |
Applications | ELISA: 0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture), Western Blot: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NRG1 Monoclonal Antibody (147705). The neuregulins are a family of ErbB/HER ligands encoded by four genes. Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural func |
Immunogen | n/a |
Other Names | Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, NRG1, GGF, HGL, HRGA, NDF, SMDF |
Gene, Accession # | Entrez: 3084; Uniprot: Q02297 |
Catalog # | MA5-23776 |
Price | |
Order / More Info | NRG1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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