产品详情 |
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Antigenic Specificity | NRG3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 5 µg/mL, Western Blot: 0.2-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NRG3 Polyclonal Antibody. This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 . NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated th |
Immunogen | n/a |
Other Names | NRG3, HRG3, pro-NRG3 |
Gene, Accession # | Entrez: 100065480, 100726543, 10718, 108178908, 18183, 479263, 498596, 539977; Uniprot: O35181, P56975 |
Catalog # | PA5-42602 |
Price | |
Order / More Info | NRG3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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