| 产品详情 |
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| Antigenic Specificity | 53BP2 |
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| Clone | 8H3L19 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | 53BP2 Antibody (8H3L19), ABfinity™ Rabbit Monoclonal. TP53BP2 (apoptosis-stimulating of p53 protein 2) is a regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. It regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. TP53BP2 inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. It also Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. |
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| Immunogen | n/a |
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| Other Names | ASPP2, BBP |
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| Gene, Accession # | Entrez: 7159; Uniprot: Q13625 |
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| Catalog # | 703010 |
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| Price | |
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| Order / More Info | 53BP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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