| 产品详情 |
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| Antigenic Specificity | 53BP2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | 53BP2 Polyclonal Antibody. Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. |
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| Immunogen | n/a |
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| Other Names | 53BP2, ASPP2, BBP, P53BP2, PPP1R13A, BCL2-binding protein; apoptosis-stimulating of p53 protein 2; apoptosis-stimulating protein of p53, 2; renal carcinoma antigen NY-REN-51; tumor suppressor p53-binding protein 2 |
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| Gene, Accession # | Entrez: 7159; Uniprot: Q13625 |
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| Catalog # | PA5-54468 |
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| Price | |
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| Order / More Info | 53BP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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