产品详情 |
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Antigenic Specificity | BRAF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:200-1:1,000, Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | BRAF Polyclonal Antibody. B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
Immunogen | n/a |
Other Names | B-Raf proto-oncogene serine/threonine-protein kinase; p94; v-Raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1; RAFB1; |
Gene, Accession # | Entrez: 673; Uniprot: P15056 |
Catalog # | A301-695A |
Price | |
Order / More Info | BRAF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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