产品详情 |
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Antigenic Specificity | B-Raf |
Clone | 1H12F1, 1H12G10,1F12F11C9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | B-Raf Monoclonal Antibody (1H12F1, 1H12G10,1F12F11C9). This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identifie |
Immunogen | n/a |
Other Names | BRAF |
Gene, Accession # | Entrez: 673; Uniprot: P15056 |
Catalog # | MA5-15317 |
Price | |
Order / More Info | B-Raf Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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