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Antigenic Specificity | CD41a |
Clone | eBioMWReg30 (MWReg30) |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, kappa |
Format | fluorescein (FITC) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 0.125 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), FITC, eBioscience™. CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, an |
Immunogen | n/a |
Other Names | BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B |
Gene, Accession # | Entrez: 16399; Uniprot: Q9QUM0 |
Catalog # | 11-0411-82 |
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Order / More Info | CD41a Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10397735, 20385801, 20637061, 20833981, 21680798, 21989919, 22628281, 22996659, 23940756, 23993099, 24162846, 24407241, 24532804, 24697684, 24829209, 25139854, 25437431, 25866967, 26148065, 26527618, 26601269, 26891705, 26912146, 27111842, 27428424, 27453007, 27689744, 28218906, 28963568, 29202466, 29239838, 29361560, 29555020, 29625072, 29765026 |
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