| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD41a |
|---|
| Clone | eBioMWReg30 (MWReg30) |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | unconjugated, functional grade |
|---|
| Size | 500 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Functional Grade, eBioscience™. CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thromb |
|---|
| Immunogen | n/a |
|---|
| Other Names | BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B |
|---|
| Gene, Accession # | Entrez: 16399; Uniprot: Q9QUM0 |
|---|
| Catalog # | 16-0411-85 |
|---|
| Price | |
|---|
| Order / More Info | CD41a Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 10397735, 21645356, 21989919, 22628281, 22996659, 23736886, 23748430, 23795291, 23940756, 24162846, 24407241, 24829209, 25025394, 25139854, 26527618, 26891705, 26912146, 27428424, 27453007, 27689744, 27783593, 28218906, 28963568, 29239838, 29361560, 29555020 |
|---|
| 产品资料 |
|
|