产品详情 |
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Antigenic Specificity | CD41a |
Clone | eBioMWReg30 (MWReg30) |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, kappa |
Format | Super Bright 645 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry: 1 µg/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), Super Bright 645, eBioscience™. CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thromb |
Immunogen | n/a |
Other Names | Itga2b |
Gene, Accession # | Entrez: 16399; Uniprot: Q9QUM0 |
Catalog # | 64-0411-82 |
Price | |
Order / More Info | CD41a Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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