产品详情 |
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Antigenic Specificity | EGF |
Clone | 3A8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | biotin conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 0.125-0.25 µg/mL, Immunocytochemistry: 1:50, Immunofluorescence: 1:50, Western Blot: 1:1000 - 1:5000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EGF Monoclonal Antibody (3A8), Biotin. EGF (Epidermal growth factor) exerts its actions by binding to the EGF Receptor, a 170 kDa protein kinase. Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family members. Each dimeric receptor complex initiates a distinct signaling pathway by recruiting different Src homology 2 (SH2) containing effector proteins. EGF is far and wide expressed in kidney, cerebrum, prostrate and salivary glands. EGF acts as a potent mitogenic factor and the phosphorylated receptor recruits adapter proteins like GRB2 that activates complex downstream signaling cascades. EGF activates at lea |
Immunogen | n/a |
Other Names | HMGF (human milk growth factor), PGF (prostatic growth factor), tooth-lid factor, Urogastrone |
Gene, Accession # | Entrez: 1950; Uniprot: P01133 |
Catalog # | M806B |
Price | |
Order / More Info | EGF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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