产品详情 |
Edit |   |
Antigenic Specificity | EGF |
Clone | S-21 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 250 µg |
Concentration | n/a |
Applications | ELISA: Assay dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EGF Monoclonal Antibody (S-21). EGF (Epidermal growth factor) exerts its actions by binding to the EGF Receptor, a 170 kDa protein kinase. Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family members. Each dimeric receptor complex initiates a distinct signaling pathway by recruiting different Src homology 2 (SH2) containing effector proteins. EGF is far and wide expressed in kidney, cerebrum, prostrate and salivary glands. EGF acts as a potent mitogenic factor and the phosphorylated receptor recruits adapter proteins like GRB2 that activates complex downstream signaling cascades. EGF activates at least 4 ma |
Immunogen | n/a |
Other Names | Epidermal Growth Factor, URG, Urogastrone |
Gene, Accession # | Entrez: 1950; Uniprot: P01133 |
Catalog # | MA1-21364 |
Price | |
Order / More Info | EGF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|