| 产品详情 |
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| Antigenic Specificity | PCMT1 |
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| Clone | OTI4A4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PCMT1 Monoclonal Antibody (OTI4A4). Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form. |
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| Immunogen | n/a |
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| Other Names | PIMT, L-isoaspartyl protein carboxyl methyltransferase, protein L-isoaspartyl/D-aspartyl methyltransferase, protein-L-isoaspartate(D-aspartate) O-methyltransferase, protein-beta-aspartate methyltransferase |
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| Gene, Accession # | Entrez: 5110; Uniprot: P22061 |
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| Catalog # | MA5-27235 |
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| Price | |
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| Order / More Info | PCMT1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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