| 产品详情 |
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| Antigenic Specificity | SIRT6 |
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| Clone | polyclonal |
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| Host Species | Chicken |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 0.5-1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIRT6 Polyclonal Antibody. The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian a |
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| Immunogen | n/a |
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| Other Names | SIR2L6; NAD-dependent deacetylase sirtuin-6; SIR2-like protein 6; sir2-related protein type 6; sirtuin type 6 |
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| Gene, Accession # | Entrez: 299638, 50721, 51548; Uniprot: P59941, Q8N6T7 |
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| Catalog # | PA5-20967 |
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| Price | |
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| Order / More Info | SIRT6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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