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| Antigenic Specificity | SIT |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIT Polyclonal Antibody. SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in signal transduction. Hubener et al. (2001) determined that the SIT gene contains 5 exons and spans 1.8 kb of genomic DNA. The SIT promoter demonstrated strong transcriptional activity and potential binding sites for both ubiquitous and lymphoid-specific transcription factors. |
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| Immunogen | n/a |
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| Other Names | MGC125908, MGC125909, MGC125910, RP11-331F9.5, SIT |
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| Gene, Accession # | Entrez: 27240; Uniprot: Q9Y3P8 |
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| Catalog # | PA5-53825 |
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| Price | |
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| Order / More Info | SIT Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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