产品详情 |
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Antigenic Specificity | SIX5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIX5 Polyclonal Antibody. Six5 (homeobox protein SIX5), also known as SIX5, BOR2 or DMAHP (DM locus-associated homeodomain protein), is a transcription factor that is expressed in various structures of the adult eye. Localized to the cytoplasm in early development and to the nucleus in the later stages of development,Six5 is involved in regulation of organogenesis and in maintenance of retinal formation. Six5 is able to bind the 5'-TCA[AG][AG]TTNC-3' DNA sequence found in the myogenin and IGFBP5 promoters and, through this binding, can control transcription of the associated mRNA. Six5 is regulated via association with DACH1 (dachshund homolog 1) and is co-activated by the EYA (eyes absent) proteins. Defects in the gene encoding Six5 are th |
Immunogen | n/a |
Other Names | Homeobox protein SIX5; DM locus-associated homeodomain protein; Sine oculis homeobox homolog 5; SIX5; DMAHP |
Gene, Accession # | Entrez: 147912, 20475, 308406; Uniprot: P70178, Q8N196 |
Catalog # | PA5-75417 |
Price | |
Order / More Info | SIX5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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