产品详情 |
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Antigenic Specificity | NUP214 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 10 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:500, Immunofluorescence: 1:100-1:500, Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NUP214 Polyclonal Antibody. Calcineurin is a widely distributed Ser/Thr, calcium and calmodulin-dependent protein phosphatase. It mediates the immunosuppressive actions of drugs such as FK506 and cyclosporin, and has also been implicated in a number of calcium-sensitive pathways in the nervous system. Calcineurin has been found to be associated with other proteins, such as calmodulin, FKBP12, the ryanodine receptor, inositol 1,4,5-trisphosphate, and a recently identified protein, calcineurin inhibitor (cain). Cain has been shown to bind calcineurin through its C-terminal tail. Recent studies have shown cain to bind to both amphiphysin 1 and calcineurin simultaneously and therefore acts as a physiological inhibitor of calcineurin. The bindin |
Immunogen | n/a |
Other Names | Calcineurin Inhibitor |
Gene, Accession # | Entrez: 8021; Uniprot: P35658 |
Catalog # | IHC-00103-T |
Price | |
Order / More Info | NUP214 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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