产品详情 |
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Antigenic Specificity | SENP2 |
Clone | OTI3D3 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate |
Isotype | IgG2a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Flow Cytometry: 1:100, Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SENP2 Monoclonal Antibody (OTI3D3). SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the GG region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates. |
Immunogen | n/a |
Other Names | AXAM2, SMT3IP2, SMT3-specific isopeptidase 2, SUMO1/sentrin/SMT3 specific protease 2, sentrin-specific protease 2, sentrin/SUMO-specific protease SENP2 |
Gene, Accession # | Entrez: 59343, 700717; Uniprot: Q9HC62 |
Catalog # | MA5-26376 |
Price | |
Order / More Info | SENP2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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