| 产品详情 |
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| Antigenic Specificity | SCO1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SCO1 Polyclonal Antibody. Synthesis of cytochrome c oxidase 1 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO1 and SCO2 are dependent on copper ion binding. Mutations in either gene can lead to cytochrome c oxidase respiratory chain defects, with a missense mutation in human SCO1 (P174L) associated with a fatal neonatal hepatopathy when the second allele is also non-functional, suggesting the pathology is due to loss of function. It has |
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| Immunogen | n/a |
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| Other Names | SCO cytoChrome oxidase deficient homolog 1 (yeast), SCOD1 |
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| Gene, Accession # | Entrez: 6341; Uniprot: O75880 |
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| Catalog # | PA5-54452 |
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| Price | |
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| Order / More Info | SCO1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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