| 产品详情 |
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| Antigenic Specificity | SCUBE1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, guinea pig, human, mouse, rabbit, rat, zebrafish |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1.0 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SCUBE1 Polyclonal Antibody. SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice. |
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| Immunogen | n/a |
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| Other Names | signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide-CUB domain-EGF-related 1 |
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| Gene, Accession # | Entrez: 100071128, 100354249, 100722542, 315174, 523518, 609479, 64706, 797832, 80274; Uniprot: Q6NZL8, Q8IWY4 |
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| Catalog # | PA5-70696 |
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| Price | |
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| Order / More Info | SCUBE1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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