| 产品详情 |
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| Antigenic Specificity | SCUBE1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SCUBE1 Polyclonal Antibody. SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice. |
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| Immunogen | n/a |
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| Other Names | signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide-CUB domain-EGF-related 1 |
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| Gene, Accession # | Entrez: 80274; Uniprot: Q8IWY4 |
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| Catalog # | PA5-20990 |
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| Price | |
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| Order / More Info | SCUBE1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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