| 产品详情 |
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| Antigenic Specificity | GPS2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GPS2 Polyclonal Antibody. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. |
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| Immunogen | n/a |
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| Other Names | AMF-1; GPS-2 |
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| Gene, Accession # | Entrez: 2874; Uniprot: Q13227 |
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| Catalog # | PA5-66932 |
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| Price | |
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| Order / More Info | GPS2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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