| 产品详情 |
| Edit |   |
|---|
| Product Name | Ku-0060648 |
|---|
| Description | Purity >98%. Ku-0060648 is an ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK) and an inhibitor of PI3K. In a cell-free assay, it has IC50 s of 5, 4, 0.5, 10,000 nM for PI3K. Ku-0060648 is useful for Cas9 editing due to its DNA-PK inhibition, which reduces the frequency of non-homologous end joining and increases homology-directed recombination. It also shows promise in cancer research in vitro and in vivo . |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 4-ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide |
|---|
| Gene, Accession, CAS # | CAS: 881375-00-4 |
|---|
| Catalog # | LS-H8374 |
|---|
| Price | |
|---|
| Order / More Info | Ku-0060648 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|