| 产品详情 |
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| Antigenic Specificity | CD45RO |
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| Clone | UCHL-1 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5-1 µg/test, Immunohistochemistry (Paraffin): 1:200-1:400, Western Blot: 1:1-1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD45RO Monoclonal Antibody (UCHL-1). CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the |
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| Immunogen | n/a |
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| Other Names | B220, CD45, CD45R, GP180, LCA, LY5, T200 |
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| Gene, Accession # | Entrez: 19264, 24699, 5788; Uniprot: P04157, P06800, P08575 |
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| Catalog # | MA5-11532 |
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| Price | |
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| Order / More Info | CD45RO Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10220446, 11359851, 14687617, 15948236, 16148405, 16888031, 16919035, 17108109, 18505436, 18685486, 18694680, 20534675, 22035150, 22238455, 22335593, 23130116, 2423439, 24448708, 24765148, 26014097, 27650547, 27785783, 28456661, 9498785 |
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