| 产品详情 |
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| Antigenic Specificity | ICAM-3 |
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| Clone | MEM-171 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ICAM-3 Monoclonal Antibody (MEM-171). CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in |
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| Immunogen | n/a |
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| Other Names | CD50, CDW50, ICAM-R, ICAM-3, intercellular adhesion molecule-3 |
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| Gene, Accession # | Entrez: 3385; Uniprot: P32942 |
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| Catalog # | MA1-19191 |
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| Price | |
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| Order / More Info | ICAM-3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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