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| Antigenic Specificity | Phospho-GABBR2 (Ser783) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 1:500, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-GABBR2 (Ser783) Polyclonal Antibody. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. It has recently been demonstrated that AMPK binds directly to GABAB receptors and phosphorylates S783 in the cytoplasmic tail of the R2 subunit and that S783 plays a critical role in enhancing neuronal survival after ischemia as phosphorylation of S783 is evident in many brain regions and is increased dramatically after ischemic injury to the brain |
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| Immunogen | n/a |
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| Other Names | GABA BR |
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| Gene, Accession # | Entrez: 83633; Uniprot: O88871 |
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| Catalog # | PA1-4705 |
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| Price | |
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| Order / More Info | Phospho-GABBR2 (Ser783) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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