| 产品详情 |
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| Antigenic Specificity | PHIP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PHIP Polyclonal Antibody. PHIP (pleckstrin homology domain interacting protein), also known as ndrp or WDR11, is a 1,821 amino acid protein that contains eight N-terminal WD40 repeats and two bromodomains. It is expressed in skeletal muscle (localizing to the cytosol and nucleus) and primary beta cells (localizing to the nucleus) and acts as a transcriptional activator. PHIP is known to interact with various members of the insulin receptor substrate (IRS) family. The IRS family of proteins mediate insulin receptor signaling and play an important role in insulin-producing beta cell proliferation and survival. PHIP specifically associates with the PH domain of IRS-1 and may function to link IRS-1 to insulin receptors, indicating a vital role |
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| Immunogen | n/a |
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| Other Names | PH-interacting protein; PHIP; IRS-1 PH domain-binding protein; WD repeat-containing protein 11; PHIP; WDR11 |
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| Gene, Accession # | Entrez: 55023, 83946; Uniprot: Q8VDD9, Q8WWQ0 |
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| Catalog # | PA5-77167 |
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| Price | |
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| Order / More Info | PHIP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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