产品名称 Phospho-Ku70 (Ser5) Antibody from INVITROGEN ANTIBODIES
产品货号 PA5-40247
产品价格 现货询价,电话:010-67529703
产品规格 100 µl
产品品牌 INVITROGEN ANTIBODIES
产品概述
产品详情
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Antigenic SpecificityPhospho-Ku70 (Ser5)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatpurified
Size100 µl
Concentrationn/a
ApplicationsWestern Blot: 1:500-1:2000
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DescriptionPhospho-Ku70 (Ser5) Polyclonal Antibody. Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together. The assembly of the DNA-PK com
Immunogenn/a
Other NamesXRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
Gene, Accession #Entrez: 25019, 2547; Uniprot: P12956
Catalog #PA5-40247
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Order / More InfoPhospho-Ku70 (Ser5) Antibody from INVITROGEN ANTIBODIES
Product Specific Referencesn/a
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