产品详情 |
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Antigenic Specificity | Phospholamban |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 3.75 µg/mL, peptide-ELISA: 1:8000, Western Blot: 0.01-0.03 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospholamban Polyclonal Antibody. The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Capump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. |
Immunogen | n/a |
Other Names | PLN; phospholamban; CMD1P; PLB; cardiac phospholamban; CMH18 |
Gene, Accession # | Entrez: 5350, 64672; Uniprot: P26678, P61016 |
Catalog # | PA5-19351 |
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Order / More Info | Phospholamban Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 26791827 |
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