产品详情 |
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Antigenic Specificity | SnoN |
Clone | OTI2C9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SnoN Monoclonal Antibody (OTI2C9). Principal Names: SnoN; SNO; SKI-like; Ski-related Oncogene; SnoA; SKIL Official Gene Symbol- SKIL Gen Bank Accession Number- NP_005405 Gene ID- 6498(Human) 20482 (mouse)Gene Map Locus- 3q26 (human) SnoN, an 80 KDa protein, is a member of ski family of nuclear proto-oncogenes involved in regulation of cellular transformation and differentiation. Primarily expressed in two isoforms, SnoN is localized in cytoplasm in normal tissues and non-tumorigenic primary epithelial cells. In cancer tissues or cells, SnoN is exclusively localized in the nucleus. It plays a vital role in inhibition of cell cycle arrest induced by TGF-beta. Upon morphological differentiation or cell-cycle arrest, SnoN translocates into the |
Immunogen | n/a |
Other Names | SNO, SnoA, SnoI, SnoN; ski-like protein; ski-related oncogene snoN |
Gene, Accession # | Entrez: 6498; Uniprot: P12757 |
Catalog # | MA5-26387 |
Price | |
Order / More Info | SnoN Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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