产品详情 |
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Antigenic Specificity | SnoN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1-3 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SnoN Polyclonal Antibody. Principal Names: SnoN; SNO; SKI-like; Ski-related Oncogene; SnoA; SKIL Official Gene Symbol- SKIL Gen Bank Accession Number- NP_005405 Gene ID- 6498(Human) 20482 (mouse) Gene Map Locus- 3q26 (human) SnoN, an 80 KDa protein, is a member of ski family of nuclear proto-oncogenes involved in regulation of cellular transformation and differentiation. Primarily expressed in two isoforms, SnoN is localized in cytoplasm in normal tissues and non-tumorigenic primary epithelial cells. In cancer tissues or cells, SnoN is exclusively localized in the nucleus. It plays a vital role in inhibition of cell cycle arrest induced by TGF-. Upon morphological differentiation or cell-cycle arrest, SnoN translocates into the nucleus, bin |
Immunogen | n/a |
Other Names | SKIL,SnoN |
Gene, Accession # | Entrez: 114208, 20482, 6498; Uniprot: P12757, Q60665 |
Catalog # | PA1-41293 |
Price | |
Order / More Info | SnoN Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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