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| Antigenic Specificity | Phospho-Leptin Receptor (Tyr986) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-Leptin Receptor (Tyr986) Polyclonal Antibody. The leptin (OB-R) receptor is a member of the cytokine receptor superfamily which plays an important role in mammalian body weight homeostasis and energy balance. Ligand-induced activation of the OB-R by the adipose tissue-secreted hormone, leptin, appears to activate downstream signaling events through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway. Leptin can homo-dimerize OB-R extracellular domains while downstream signaling events are initiated upon homo-dimerization of OB-R intracellular domains. Several isoforms of the OB-R which differ in length and signaling capabilities have been reported. RNA transcripts encoding the OB-R long form have b |
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| Immunogen | n/a |
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| Other Names | HuB219.2 |
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| Gene, Accession # | Entrez: 3953; Uniprot: P48357 |
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| Catalog # | PA5-64634 |
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| Price | |
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| Order / More Info | Phospho-Leptin Receptor (Tyr986) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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