产品详情 |
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Antigenic Specificity | GATA2/GATA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GATA2/GATA3 Polyclonal Antibody. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (199 |
Immunogen | n/a |
Other Names | GATA-binding factor 3, GATA3, 2625, GATA3, 131320, P23771, HDR, MGC2346, MGC5199, MGC5445 |
Gene, Accession # | Entrez: 14461, 14462, 2624, 2625; Uniprot: O09100, P23769, P23771, P23772 |
Catalog # | PA5-36109 |
Price | |
Order / More Info | GATA2/GATA3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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