产品详情 |
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Antigenic Specificity | AS160 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 10 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AS160 Polyclonal Antibody. TBC1D4, also known as the Akt substrate AS160, was initially identified as an Akt substrate containing a GTPase-activating domain that regulates GLUT4 trafficking, with activation following insulin stimulation. TBC1D4 truncations in humans is a major cause of dominant inherited insulin resistance. The loss of TBC1D4 results in the accumulation of GLUT4 in compartments that are primed for fusion in basal adipocytes. |
Immunogen | n/a |
Other Names | TBC1D4, TBC1 domain family member 4, TBC Tre-2, BUB2, CDC16 domain-containing protein, AS160, Acrg embryonic lethality mouse minimal region ortholog |
Gene, Accession # | Entrez: 9882; Uniprot: O60343 |
Catalog # | PA5-34524 |
Price | |
Order / More Info | AS160 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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