| 产品详情 |
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| Antigenic Specificity | MCFD2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:20-1:50 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MCFD2 Polyclonal Antibody. This gene encodes a soluble luminal protein with 2-calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 that facilitates the transport of coagulation factors V and VIII from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment. Mutations in this gene cause combined deficiency of FV and FVIII, a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon- |
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| Immunogen | n/a |
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| Other Names | F5F8D, F5F8D2, LMAN1IP, SDNSF, multiple coagulation factor deficiency protein 2, neural stem cell derived neuronal survival protein, neural stem cell-derived neuronal survival protein |
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| Gene, Accession # | Entrez: 90411; Uniprot: Q8NI22 |
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| Catalog # | PA5-56985 |
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| Price | |
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| Order / More Info | MCFD2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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